Louisville at Syracuse

Experimental model: market-anchored, it moves the line only slightly and matched the closing line in the 2024-25 backtest rather than beating it. A second opinion, not a pick. Odds are shown for information only and change quickly; confirm the price at the sportsbook. There is no gambling offered on this site. If you or someone you know has a gambling problem, call or text 1-800-MY-RESET.

Louisville 34, Syracuse 26 on Oct 17, 2026. Against the closing line, Syracuse covered; the total went over. Box score context, records against the spread and the head-to-head series.

Game details

  • Kickoff (ET): Saturday, October 17, 2026, 7:30 PM
  • Venue: JMA Wireless Dome
  • Consensus spread: Syracuse +14.5
  • Consensus total: 56
  • Moneyline: Syracuse +422 / Louisville -585
  • Model projection (experimental): Louisville 34.7 - Syracuse 20.6; Louisville wins 82%
  • Model fair line (experimental): Syracuse +14, total 55.5
  • Final: Louisville 34, Syracuse 26
  • Against the spread: Syracuse covered
  • Total: Over

Team comparison

TeamRecordConfATSAPSP+
Louisville7-36-26-4-017.7
Syracuse5-53-56-4-0-2.7

Louisville recent games

DateOpponentResultScore
Oct 9vs Florida StateW44-20
Oct 3at NC StateL28-31
Sep 26vs Wake ForestL27-30

Syracuse recent games

DateOpponentResultScore
Oct 10at VirginiaL25-28
Oct 3at UConnW42-41
Sep 17at PittsburghL13-27

Head-to-head (last 10 meetings)

SeasonHomeAwayScore
2022SyracuseLouisville31-7
2021LouisvilleSyracuse41-3
2020LouisvilleSyracuse30-0
2019LouisvilleSyracuse56-34
2018SyracuseLouisville54-23
2017LouisvilleSyracuse56-10
2016SyracuseLouisville28-62
2015LouisvilleSyracuse41-17
2014SyracuseLouisville6-28
2012SyracuseLouisville45-26

Data provided by CollegeFootballData.com