Wake Forest at No. 16 Louisville

Experimental model: market-anchored, it moves the line only slightly and matched the closing line in the 2024-25 backtest rather than beating it. A second opinion, not a pick. Odds are shown for information only and change quickly; confirm the price at the sportsbook. There is no gambling offered on this site. If you or someone you know has a gambling problem, call or text 1-800-MY-RESET.

Wake Forest at Louisville on Sep 26, 2026. The consensus line is Louisville -13, total 58.0. Experimental model projection: Wake Forest 22.4, Louisville 35.0. Best prices across regulated sportsbooks, fair lines and each team's form.

Game details

  • Kickoff (ET): Saturday, September 26, 2026, 12:00 PM
  • Venue: L&N Federal Credit Union Stadium
  • Consensus spread: Louisville -13
  • Consensus total: 58
  • Moneyline: Louisville -529 / Wake Forest +390
  • Model projection (experimental): Wake Forest 22.4 - Louisville 35; Louisville wins 80%
  • Model fair line (experimental): Louisville -12.5, total 57.5

Team comparison

TeamRecordConfATSAPSP+
Wake Forest2-10-11-2-03.6
No. 16 Louisville2-11-03-0-0No. 1613.3

Wake Forest recent games

DateOpponentResultScore
Sep 18vs MiamiL20-33
Sep 12at PurdueW38-36
Sep 3vs AkronW38-16

Louisville recent games

DateOpponentResultScore
Sep 19vs SMUW41-31
Sep 11vs VillanovaW59-13
Sep 6at Ole MissL38-41

Head-to-head (last 10 meetings)

SeasonHomeAwayScore
2022LouisvilleWake Forest48-21
2021Wake ForestLouisville37-34
2020LouisvilleWake Forest45-21
2019Wake ForestLouisville59-62
2018LouisvilleWake Forest35-56
2017Wake ForestLouisville42-32
2016LouisvilleWake Forest44-12
2015Wake ForestLouisville19-20
2014LouisvilleWake Forest20-10
2006Wake ForestLouisville13-24

Data provided by CollegeFootballData.com